Pulmonary Drug Delivery System
Patent Information:
Filing Country: USA
Application No: 08/229600
Filing Date: 19 April 1994
Patent No: 5451569
Issue Date: 19 September 1995
 
Inventors:
Inventor 1: Dr. Michael Siu Cheung, TAM
Inventor 2: Prof. Jeffrey Tze Fei, WONG

Technology
One of the known routes for the delivery of drugs into the human or animal body is pulmonary drug delivery, for example through nasal sprays or tracheal instillation. However, such method is very wasteful and a relatively large amount of the drug is necessary to ensure that the correct dose is received by the patient. A novel technique has been developed for pulmonary drug delivery. An effective amount of a pharmaceutically active agent in the solution mixed directly with physiologically acceptable surfactant has been found to significantly increase the absorption of the pharmaceutically active agent via the pulmonary route. This invention is particularly applicable to the delivery of drugs which cannot be given orally, or which have localized action in the lung. In particular the invention may be applied to the delivery of protein-based drugs such as insulin using for therapeutic treatment of diabetes mellitus. The invention also extends to a method for the manufacture of pharmaceutical composition, comprising the pulmonary delivery of an effective amount of a pharmaceutically active agent mixed directly with a physiologically acceptable surfactant.
 
 
Potential Application   Advantage
- Anti tumor agents for therapeutic treatment of lung cancer
- Therapeutic treatment of chronic diseases such as diabetes mellitus
  1. Chronic disease can be treated with pulmonary drug delivery
2. Drugs which cannot be given orally, can be delivered
3. It can increase the absorption of drug via pulmonary drug delivery
     
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Contact information :
Ms Shirley Woo
(852) 2358 7918
cawoosw@ust.hk
HKUST R and D Corporation Ltd
http://rdc.ust.hk
(852) 2358 7917
ttcac@ust.hk
Technology Transfer Center
http://www.ttc.ust.hk/
   
香港九龍清水灣 香港科技大學
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, CLEAR WATER BAY, KOWLOON