Uses of dl-THP
Patent Information:
Filing Country: USA
Application No: 09/819367
Filing Date: 28 March 2001
Patent No: 6521634
Issue Date: 18 February 2003
 
Inventors:
Inventor 1: Mr. Sek Lun, LAW
Inventor 2: Prof. Hong, XUE

Technology
dl-THP (dl-tetrahydropalinatine) was only marketed as an herbal supplement or sleeping pill. However, a novel use of dl-THP is available now. The present invention succeeds in identifying a previously unsuggested binding partner for dl-THP, namely the BDZ (benzodiazepine) binding site of the GABAA receptor. A method of manufacture of a composition (eg. A medicament) for the treatment of CNS (central nervous system) disorders, including the treatment of anxiety and seizures, the composition comprising dl-THP is provided. Thus, the uses of dl-THP could be expanded and developed into sedative-tranquilizing, anticonvulsant or myorelaxant agents for the treatment of CNS disorders.
 
 
Potential Application   Advantage
- Potential drugs for the treatment of central nervous system disorders or memory impairment
- Potential anxiolytic, anti-convulsantor sedative-hypustic drugs
  1. New usage of dl-THP
2. Low toxicity
     
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Contact information :
Ms Shirley Woo
(852) 2358 7918
cawoosw@ust.hk
HKUST R and D Corporation Ltd
http://rdc.ust.hk
(852) 2358 7917
ttcac@ust.hk
Technology Transfer Center
http://www.ttc.ust.hk/
   
香港九龍清水灣 香港科技大學
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, CLEAR WATER BAY, KOWLOON