Apparatus and Method of Optical Imaging for Medical Diagnosis
Patent Information:
Filing Country: USA
Application No: 12/506028
Filing Date: 20 July 2009
Patent No: 8334900
Issue Date: 18 December 2012
Inventor 1: Prof. Jianan, QU
Inventor 2: Dr. Tao, WU

Cervical cancer is the second most common cancer in women worldwide. The motivation of this invention comes from the fact that the currently standard diagnosis methods, Pap smear and colposcopy, produce poor diagnostic accuracy and are not cost-effective. The primary goals of this invention are (1) to improve the accuracy of noninvasive diagnosis of early cervical cancer and (2) to significantly reduce the cost of cervical cancer diagnosis. In this invention, a novel 3-D optical imaging system based on active stereo vision and motion tracking is developed to track the motion of patient and to register the time-sequenced images of cervix recorded during the examination. This technology can quantify the acetic acid induced optical signals associated with early cancer development at cervix. The imaging system can be easily integrated with a standard commercial colposcope for the diagnosis of early cervical cancer. The results of a preliminary clinical study of 65 patients at the Prince of Wales Hospital demonstrate that the accuracy to differentiate pre-cancerous cervical tissue from normal tissue can be significantly increased. In particular, the new technology does not require extensive training to operate and holds the potential to develop a fully automated system for accurate diagnosis of early cervical cancer.
Potential Application   Advantage
- For accurate diagnosis of early cervical cancer   1. Does not require special training of operation
2. Higher accuracy
3. Lower cost
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